wouldnt bother with b650 boards if you plan to populate it and board prices are all over the place. Id only buy what you need it for for you its using 4x m.2 and 4x sata ports without anything being disabled do you need more ? or you want another m.2 and 2 more sata ports and put in another £300 ? performance wise between boards you dont get anything
ROG STRIX X670E-F GAMING WIFI , I cant seem to find any info if you have everything populated 4x m.2 two of these slots are gen 5 as well / 4x sata if it effects anything so I guess its fine but might have missed something
looking up AE9 Sound card it uses the x1 slot ? so you wouldnt be effected with the following
if you using device in PCIEX16_2 slot you have to reduce the GPU slot to x8
PCIEX16_1 Bandwidth Bifurcation Configuration
[Auto Mode] Auto-detect and switch. If PCIe device is inserted to PCIEX16_2,
switch PCIEX16_1 to x8. If no device is inserted to PCIEX16_2,
switch to PCIEX16_1 to x16.
[PCIE X16 Mode] Switch PCIEX16_1 to x16, and disable PCIEX16_2
check for yourself