Soldato
*some* people.
*some* people.
these drugs do not lend themselves well to regulation and legal consumption because the differences between a suitable active dose and a lethal dose are so close and the amoutns needed are so easily consumed.
I don't believe there is a single one, but there's a fair few in various countries. I'm just fed up with Nutt being quoted as if he's the be-all and end-all of the subject - usually by people who want their drugs legalised and Nutt supports them.
There is no "right" answer. You just listen to all the views and then try to balance pain and gain. Everything has a price: legalisation, de-criminalisation, prohibition. All of them.
I've tried MDMA once before after I did actually research it, and after that point I did sit and think yeah I now know why this is illegal.
differences between a suitable active dose and a lethal dose are so close and the amounts needed are so easily consumed.
Never heard of LD50 before. I assume this is testing on rats?
Off topic but if I ever start a death metal band, I think LD50 would be a great name.
Median lethal dose
In toxicology, the median lethal dose, LD₅₀, LC₅₀ or LCt₅₀ of a toxin, radiation, or pathogen is the dose required to kill half the members of a tested population after a specified test duration.
My point is it's extremely inconsistent and incredibly easy to get it wrong. Using the alcohol example, you have a much greater appreciation of how much you're having due to the volume/taste. Remember when alcopops become a bad 'thing' because it was argued that kids simply weren't aware of how much alcohol they were consuming? Well, things like ecstasy are the extreme end of that because it's so easy to ingest. I can totally understand why it's illegal. However, with regulation and controlled sales from licensed places I'm sure people could use them safely and responsibly. I think it would increase the number of abuse cases, but it turn it would reduce the number of alcohol abuse cases.
I don't think you can really take dosage range from rat and mice studies and then directly apply the figures into humans. Actually I know you can't it's just wrong.
Maybe my earlier suggestion should be brought in then. Use the finance from a sale to employ the people to give them out as paid prescriptions. That way you could see usage and get some metrics back to tie in with everything else to identify the problems that arise.
Legalisation and regulation is an interesting point, one I've thought about but it's such a grey area. I agree it's hard to judge what dose you are in taking and that can be part of the problem.
It is a very hard one to call. Legalising drugs could end the black market/mafia drug trade etc etc overnight for example. Which I think would be a huge step forward but then it brings in other problems as Tefal said because people most likely would all just do it and not regulate their intake. You can get ahold of drugs but there is at least some level of an entrance barrier (hard to find sometimes, legal risk, it's a bit shady etc) which puts people off so probably stops the vast majority of people using regularly. But if you could walk into a shop and buy MDMA even I admit i'd probably do it again if it was that easy to get ahold of. I would never abuse something because i'm just not like that, I don't even drink regularly but i'm in the minority.
Imagine amount of money it would save though if they did legalise drugs and put all the cartels out of business.
No,but it's safe to say that most Drugs are far less Toxic than Alcohol and can be consumed safely in appropriately measured doses.
And how the hell did that relate to my comment which was: one can not work out mg/kg LD50 doses on rats and mice and then apply that onto humans and then say a human LD50 dose will be X mg for someone of Y kg. (especially in this case where the results vary from say 100-300mg/kg depending on whether you use mice or rats.
And how the hell did that relate to my comment which was: one can not work out mg/kg LD50 doses on rats and mice and then apply that onto humans and then say a human LD50 dose will be X mg for someone of Y kg. (especially in this case where the results vary from say 100-300mg/kg depending on whether you use mice or rats.
Oh,and I do not believe that health concerns should really play into this debate,quite simply because it's people's responsibility to treat their Mind and Body right...