No one will care about this but you cannot get 91% pure MDMA. The highest purity is ~84% as the other 16% is the molar mass of HCL.
Ridiculous semantics, when someone says 100% pure they are always referring to actual product being consumed, whether it is a salt or freebase.
Well even if you were to divide that LD50 by 6, you are still looking at a single dose far greater than any person would normally take.
It's unlikely that the LD50 difference between mice and humans would be any greater than /6 as if it were, there would have been significantly more deaths and hospitalizations as a direct result of MDMA usage over the past few decades.
Difference between LD50 in rodents and humans is massive.
Take nicotine for example, in rats the LD50 is 50mg/kg in humans it's 1mg/kg.
these drugs do not lend themselves well to regulation and legal consumption because the differences between a suitable active dose and a lethal dose are so close and the amoutns needed are so easily consumed.
its hard to drink an extra 6 pints to push yourself over the edge but another pill?
Alcohol has a narrow therapeutic index, the difference between a recreational dose and a toxic one is low, it is very easy to drink an extra few shots of vodka or down a triple vodka and tango that the local nightclub is offering. Why do you think so many people end up in hospital at the weekend from alcohol poisoning or injuries due to it?
By contrast it is almost impossible to die from benzodiazepine overdose, cannabis or LSD. And the effects of opioids can be instantly reversed by naloxone, which you can't do with alcohol.
Most drugs generally have a higher therapeutic index than alcohol.