I use mine for a mix of gaming and work/productivity.
For work and productivity it's simply awesome. I also use Stardock Groupy, and Microsoft PowerToys Fancy zones to help manage the sheer real estate of screen space. Definitely check those out. I also use Stardock Fences, but that's more related to OLED burn-in concerns.
For gaming, one of the reasons I love this screen is that it's not a narrow, letterbox aspect ratio. In terms of proportions and aspect ratio, it has width, but it also has height. For the games I play (flight / space sims), this vertical dimension matters to me, a lot, it's super immersive. With a head tracking device, one could argue it's better than VR in some ways. Personally I could never get on board with narrow letterbox aspect ratios, doesn't really work for my use case or personal preferences, always felt a bit uncomfortable and restrictive, but others absolutely swear by it - so it's very much personal preference obviously.
I have read that a 48 is too big for people who are into competitive gaming such as CS:GO, as you lose detail in you peripheral vision: the bad guy might be onscreen, but he's somewhere off to the side of your focus as the screen is so big and you cannot react as you might on a 24-30 inch: depending on your distance to the screen, obviously. I am about 800-900mm from the screen generally. So I have read some go for 40-42 inch max in this case.
I also play games like ARMA3: does it matter to me if my perihperal vision is slightly compromised? No, it feels just immersive in a great way, although I am not an elite gamer or competitive. Your personal space and setup obviously matters a lot, also: if you've got a man cave / den type of a setup and you're on a sofa 2-3m away, it's obviosly a different ballgame to if it's on your desk (as mine is). So, not sure if any of this helps, but I have spent the last two years with this monitor and along the way have considered the above, a lot. Love this screen, it's awesome.