The older generation AMD CPU's responded really well to increased FSB and NB speeds. PD also benefits just not to the same degree.
It is still worth doing though.
How far you can go will depend on your MB, Sabertooths and Crosshairs which I have used can get to 300Mhz quite easily.
You have to balance the FSB clock and available multi's for the CPU, NB and RAM.
Some things you will need to establish if you want to get the most benfit from increased FSB speeds.
1: what is the MAX clock for your RAM.
Set a low CPU speed so there is no chance of it causing any errors and push your RAM clock up.
Adjust the FSB and RAM multi and keep the CPU and NB multi low whilst you do this as the test is only for the RAM.
When testing RAM clocks it is advisable to use memtest before booting into an OS as really unstable RAM can corrupt your OS.
Download memtest86+ bootable USB key version ideally.
When booted into the OS you can run a few large FFT tests in P95 to test the RAM.
I would try a Super PI 32m test first. if that fails don't bother with the P95 tests as the RAM is unstable.
You will need to increase your RAM voltage as you approach the limits of your RAM, going over 1.65v is OK but how far over depends on what you are after long term settings or bench able settings.
As you up the RAM speed you will need to slacken off the primary timings a bit.
Your standard settings at say 1600 may be 9.9.9.27 at 1866 you may have to use 9.10.10.28 for example.
Let the MB sort out the sub timings until you become more proficient, tuning the sub timings is of great benefit but will waste days of your life.
Note: If your NB speed is set too high memtest can throw up RAM errors which are actually the fault of unstable L3 cache in the NB.
2:Find your NB limits.
Keep the CPU and RAM multi's low and up the NB speed.
Test with AIDA, and P95 blend.
P95 will error very quickly with an unstable NB so no need to do any extended testing.
You will need to increase the NB voltage as you go over 2400Mhz.
Above 2700Mhz you will need a lot of NB volts, if you find you are setting greater than 1.4v to try and keep things stable I would stop.
OK for quick benches but no good for any long term stability
3: Find your MAX CPU clock.
Same drill as before keep NB and RAM multi's low to rule them out as possible causes of instability.
Using the 200Mhz base clock adjust the CPU multi up and test for stability with AIDA or similar.
Use the half multi's as well and then increase the FSB a little to find the absolute maximum CPU speed.
You will need to increase vcore as the CPU speed increases.
If you fail a test up the vcore a little until it passes.
There will come a point where increasing vcore just isn't helping any more with the CPU clocks.
You know your getting close to this wall when a minor increase in CPU speed requires a large increase in vcore.
4:Find MAX FSB
Set low multi's for CPU,NB and RAM.
You will be wanting to keep them close to stock when testing the FSB speeds so as not to have them as a possible cause of instability.
As before this is to ensure you are only Working with one variable at a time.
Up the FSB and test.
Keep upping the FSB and asjusting the other multi's as necessary to keep them within limits until you hit instability.
Now you should have found your max RAM clock, NB clock, CPU clock and FSB.
Time to play with different combinations of FSB and multi's on the CPU, NB and RAM.
You will be looking for a combination that runs your CPU, NB and RAM at close to there maximums with as high an FSB speed as you can manage.
Note: keep your HT speed down whilst testing the limits of the other clocks 2 - 2.2Ghz should be plenty.
You might want to increase the HT clock as potentially this can speed up the transfer of data over the bus to the Video Cards.
This is only really of benefit with multi card setups though as the standard HT speed is normally sufficient for single cards.
Some folks sync up the HT and NB clocks as this can increase 3d performance.