Apparently it's no hassle if you rebuy it on GOG. Download FO4, download FOLON, run FOLON installer. But I already had it on Steam.
Did you do anything to stop the frequent and apparently random CTDs with an unhandled exception?
Did you do anything to reduce the cell to cell loading times? 5 minutes 20 seconds of loading screen to go from one location to another and talk to one NPC, just to do one small step in one quest in one questline exceeds my tolerance for loading screens in game. That's not hyperbole. I timed it. Loading from one cell to another takes between 50 seconds and 2 mins 10 seconds.
Nothing specific (that I know of).
I do (did) have a few mods installed, including Buffout4 (stopped the CTD's, no longer needed if running the latest patch), Weapons Debris Crash Fix, High FPS Physics FIx.
Loading times when going through doors around 20-22 secs (on an NVMe).
Fast travel going to a new area will be around a minute or less.
If you haven't already, I wholly recommend using the Fallout 4 Tweaker (by Bilago), this enables a whole host of settings, not least of which is setting iNumHWThreads to suit how many cores your CPU has, it defaults to using one core only. I have a 12700K so it recommended a setting of 12, for example.
Not to say the game doesn't need further patching, as the devs have already said.
Before the patch, I had it in a state of no CTD's, at all. Since the patch, I don't get CTD's as such, but Every.Single.Time I start the game when awaking the PC from sleep, it will lock the PC, so I have to sign out, sign back in, and then the game will start OK.