I've had Diarra & IF Diarra before, very good, chases like a little Rotweiler, although, as I play a custom 4-1-3-2 he is the sole CDM and tires very quickly, and at 5"8 loses out on pretty much all headers coming in from GK's/long passes etc..
sub for someone else in 2nd half? or try these tips below
ive never really had a player tire apart from roberto carlos, i have learned how the stamina engine works and now know how to keep a player's stamina up and use it wisely.
i'll give you some tips now, when he doesnt have the ball, dont hold down x (normal tackle), when your holding down x, it depletes stamina, now combine this with sprinting and holding down x and the player's stamina goes straight down like crazy. so only press x when you know your within tackling distance or have a chance of getting the ball, holding it down constantly kills stamina.
another tip is, if you see your player has low stamina (look at bottom of screen, if hes green he is fine, if he's in the red then he is low, the bar depletes as you use the player), dont sprint or do anything with him, just hold back and try and slow play down (switch to someone else if you can) , sprinting with a player who is low on stamina depletes his overall stamina on a very fast basis, basically meaning he will get tired more easily for the rest of the game, so using sprint or x when they are already low, basically means your killing how useful they are going to be later on in the match and then the more you use them the more the overall stamina goes down.
so there you go, dont sprint unless you need to, dont hold down x unless your within range, and dont use a player with low stamina, switch to someone else, or hold back (jockeying them without using the jockey button).
another tip is never use 1-2 with any of your defending players.