Associate
as "manchesterjim" on Quidco has pointed out
wouldnt necessarily say it would make the game an 'easy ride' at all;
Golden guns = more fame = more side missions quicker.
War Horse = Best horse in the game - Whilst this will give you an advantage I cant see it affecting your progression through the game too much. Dont reckon it will be much different from having a faster car in gta (gets you around quicker but doesnt necessarily make things easier).
Faster dead-eye regeneration - This is perhaps the only thing that will make the game much easier, but that depends on just how much faster it recharges. At any rate, dead-eye is an ability that you trigger yourself so you dont have to spam it.