New Vegas on the other hand didn't give me any hassle at all.
Same here. Had 1 vanilla bug in hundreds of hours of gameplay, and that happened less than an hour in to a game(Half of the residents of Goodsprings decided to trek to Black Mountain!). NV is the most stable Bethesda game for me, and I am amazed how you can keep throwing mods at it, and it just eats them up. Don't think I've ever had a CTD...this is more to do with the quality of mods created though imo, which was at its highest in NV.