I have Di2 and it works perfect on the bike. On the Neo the top and bottom cogs are fine but as I move into the middle of the cassette it starts clicking and then misses one gear on the way down and back up. I've tried the various spacer options but with no improvement.I ca never get my index perfect on the Neo when swapping from the road wheel which is spot on. Guess it's due to the spacer and hub etc but it's a pain.
I have a 2x new cassettes and chain coming this week so i'm hoping that fixes it.