Yeah it varies massively, it really comes down to the board AND understanding how your board works. I'm fairly use to Asus Z boards now so i have a fair understanding on what they do and how it functions. For anyone else overclocking on a Asus board i would highly recommd disabling asus multi core enhancement as it pushes way too much voltage.
For instance, if i left that on and set my vcore to auto without any offsets and left the overclocking to auto where Asus will overclock it for you, the board will automatically try and push 5.4ghz at 1.5v which absolutely destroys my temps, easily hits 100c+ instantly.
I haven't tried for 5.3ghz yet but i don't think its feasible, will probably need 1.4v or higher to reach that and temps will be above 90c at full load all cores loaded.
I've also disabled thermal velocity boost, i found that was causing some stability issues. No idea why as it shouldn't if im running a manual overclock.
I've also pushed my SA VID voltage to 1.265v for better stability as well, this might help you. Worth tinkering with if you can post but can't get it stable on a bench.