I ain't no expert but I hold fade for as long as I can - I use it much more for escape than for offence. Dodging the Hog hook, reaper ulti, Junk tyre etc - I would say I'm 50/50% healing/damage orbs. Also using Ult, I tend to hold for extreme healing situations like last second holds etc or use it after/with other ults like Reins hammer/Zayra grav etc. On it's own the ulti is easy to dodge by the other team.
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