Next, let’s address beta alanine. I categorized beta alanine as a conditionally beneficial supplement because it only has a small performance enhancing effect when efforts reach a duration of at least 60 seconds [
18]. So, for powerlifters, Olympic lifters, and anyone training primarily for strength, it doesn’t serve a purpose. With the typical tempo that most people lift with, you’d need to be doing sets of 15 reps+ to get a benefit from beta alanine. So perhaps bodybuilders could benefit from taking beta alanine, but only if they are doing a large volume of high rep work. However, there is not a requisite rep range for hypertrophy training per se. Equal hypertrophy can be achieved with both 10RM and 3RM loads given equated volume; the only advantage of moderate repetition ranges (8-12) is that it is easier to accumulate volume compared to using heavier loads which requires more sets, long rest periods and thus takes much longer [
19]. Simply put, to optimize hypertrophy enough volume needs to be performed with loads that are “heavy enough”, because high rep, low load sets (20RM+) don’t produce as much muscle growth as moderate and heavy loads when volume is equated [
20]. In fact, to get comparable muscle growth to that which can be achieved with heavier loads, one may have to perform three times the volume with high repetition low load training [
21]. Therefore, I would argue that only during phases of training where high reps (15+) are emphasized, or potentially when one is performing HIIT cardio using intervals lasting 60 seconds or longer, would it be advisable to consider beta alanine supplementation.