Warhammer 40K: Rogue Trader.
Really liked this game. A well-worked crafting of the 40k grimdark setting, and even though I know a bit about the lore, the game had some moments that brought out the desolation and brutality of the 40k universe in ways that still surprised me. As seems par for the course with Owlcat games, the levelling and stat/skill system is either beautifully or horribly deep, depending on your taste. I had 112 hours in my run, and I don't think it would be totally unrealistic to say that possibly a quarter of that was time spent in the levelling process - reading all of the skill descpriptions, checking synergies with gear and existing or future skills, allocating stat points, etc. I loved all that as was happily able to construct a deliciously overpowered MC and retinue.
Also part of the Owlcat experience is that alongside the depth or writing, world-crafting, detailed RPG mechanics and all the general good stuff, there's some element(s) that I'm going to like a lot less. Here it was the space map and space combat. Not entirely bad, but just far less engaging and a bit annoying. I guess the way timed events work with warp jumps was behind the mechanic that means you have to make each jump on a cross-system journey from star system to star system individually, but hooo boy was that annoying! Colony management was an okay bolted-on element, but felt a bit clumsily integrated really. Ship combat was too shallow and also too long-winded for my liking. Plus the game kept randomly de-populating my ship systems, so I had to quit the battle, go back to the save just before and put the appropriate crew members back in post manually. Ugh!
The good far, far outweighed the bad, though, and even after such a mammoth playthrough I am still missing the game a few days after finishing it. 8.5/10 (would have been even higher but for the odd minor bug still in the game and the space navigation/combat bits).