I had a chance to try out the TP-Link AC1750/RE450 access point at my parent's house yesterday. The powerline adapters are Netgear PL1000 https://www.netgear.co.uk/home/products/networking/powerline/PL1000.aspx and the one in the living room is wired to a Tenda G1005D 5-port Gigabit Switch. I've got the same switch and I recall I had some issues using it with a Raspberry Pi running Moonlight to stream from my PC to my TV which I fixed by replacing it with a Trendnet TEG S50g https://www.trendnet.com/products/product-detail?prod=510_TEG-S50G . So I may need to replace my parent's one too but there seems to be another problem that's unrelated to that.
I had the AP set up with only the 5Ghz band on and wired to the switch and the Quest 2 connected to that fine but in Alcove I tried to play some of the travel videos from Paris and Amsterdam and they just kept freezing for about 10 seconds every 5 seconds. It was the data stream that was freezing, as I could still rotate the view to look around the still image, so the app wasn't crashing. I had no such problems playing these videos with the Quest 2 connected to the AP in my house, with it wired directly to my BT Smarthub.
So I tried using the AC1750 as a WiFi repeater instead of an AP, extending just the 5Ghz signal. That reduced the speed to 150Mps (which doesn't really matter for this test, as my Dad's broadband is only 100Mbps) but it took the Tenda switch and the powerline adapters out of the equation and I still had the same problem with the video playback freezing in Alcove.
I also tried connecting the Quest 2 directly to the Wifi on the Virgin Media hub upstairs, on the 5Ghz band. The signal's not great downstairs, which is why I bought the AC1750 but by the living room door its OK and I still had the same problem with the Alcove videos freezing.
So I'm wondering if there's an issue with the Virgin Media router/modem causing this. If so, it won't make any difference what other equipment I use. What diagnostics could I do to find out if there is a problem with the router? My parents haven't had any problems streaming online video from Amazon and iPlayer to their WiFi connected TV in the bedroom upstairs, nor with offline video stored on the PC streamed via Plex and the powerline adapters to the TV downstairs, so I don't really see how there could be a problem with the VM router that would only cause problems with Quest apps playing online videos but equally I don't see what else it could be, in light of the things that I tried.
There are a lot of different ways to test things. What I would do first is bring the Quest 2 upstairs and connect it to the Main Router directly using 5Ghz. See what happens.
If that works ok, you should bring the TP-Link Ac1750 upstairs as well. Connect it to the switch with a Cat 5e cable. Unplug everything else from the Switch apart from the PC, Main Router and the AC1750. Connect the Quest 2 to the AC1750 using 5Ghz. Again see what happens.
If that also works ok, then you are down to two things. Either the Wiring in the house or the Homeplugs aren't good enough to supply enough bandwidth for the Quest 2. You can get by on speeds slower than 100Mbps for streaming movies, but you need much faster speeds for the Quest 2 to work.