I wouldn't worry about a DVD drive.
As to the outlook, well if you don't 'live' for storage it's not a big deal.
But if you do then for example you lose the option to use those 4 ports for a nice big RAID array. Also for any modern system you've lost half your maximum storage capacity based on the assumption that after DVD and SSD you've dropped from 6 useable ports to 3.
Anyone who is that into storage is also likely to be putting the throughput through the ports. For example imagine you did have a RAID array on those 4 SATA II ports, then a drive fails which means huge quantities of data will be chucked about when you replace the drive and the RAID rebuilds... which then causes a SATA port to fail mid write. ( plus the fact that the array would take forever rebuilding due to the slowed performance ).
I didn't buy a high end product for bling, I bought it because I needed the features.