Caporegime
Yes I've been on 3 different meds, as for the reclusiveness it's more that it just build up over time. It wasn't any reason, it's I just stopped going out and then after awhile that just became the norm.
So absolutely no issues before then such as problems socialising, issues with mood and focusing on things? Did you have any ambitions for a career etc?
If it’s genuinely treatment resistant then it could be something else at play like neurodivergence.