If you're not getting any stuttering, just double check that you've got auto-save enabled, cos thats when i tend to see it.
Aaaand ive got 3.67GB worth of save files

Maybe 2min autosave & unlimited saves needs a rethink

5min & 50 saves should be reasonable (would prefer 25 i think, cos 1hr paused might use 12 saves. Not sure.)
~40mb per file, and the 100k population file is 66mb, so bare that in mind if you've set autosave. When you look at the save screen, it only shows the city name and just 1 file per map. However if you go to load, it shows the autosaves there.
Anyone got anything they fancy showing off yet? I've only got to 'Tiny Town' aka Tier 5 so far using an ugly grid layout to build progress, and have now started terraforming and laying out in the surrounding area and will bulldoze the old zone to transition over (will move the utilities/services over).
Dont suppose anyone knows where footpaths are?
Edit: WTF are they doing in the Terraforming panel??
Oh, I also saw that theres 8 free "Region Packs" coming - Japan, UK, East US, West-US, China, France, East-EU & Germany. They showed early versions of a couple of models towards the end of todays stream. Im not sure if these are the same as the EU & NA themes, or just individual monuments, but it'd be very odd if they were just monuments considering that was the pre-order bonus. I'd love to see them do a Mediterranean theme, the light walls & bright terracotta tiles, and then throw in some warmer climate trees & eventually beaches.