I got a Mizuno hybrid a couple of months ago and the first few times I took it out I couldn't hit it at all. Then it dawned on me, I was trying to hit it like a fairway wood, sweeping the ball. As soon as I changed and started hitting it just as if it was an iron I hit it perfectly, and in fact it's now the best club in my bag!
So, if you're struggling, try thinking of it as an iron and see how it goes.
I also found addressing the ball as you would an iron improved hitting the ball with my hybrid. Great club once you are hitting the ball correctly.