Supplements the debate/discussion thread

I already use Reflex Whey. But need something to help gain some weight and use as a mid-morning/afternoon meal.
So a whey shake is just as good?

Add some MCT and / or some carbs to that whey if you want to gain weight.

Or, just have another meal in the day - like some nuts and fruits, peanut butter, etc... or heck, chicken/rice/broccoli/meat/fish/anything! :p
 
Out of interest, for those of you who really want to experiment, have you tried using steroids?

I never wanted to become huge, but I know there are some on this forum who would love to have the American wrestler, beefcake look. Almost certainly, to be huge AND ripped, chemical assistance will be required. Have any of you gone down that road and if so, what were the affects?

SPW already answered this from a Don's point of view.

However, why even suggest experimenting with exogenous hormones - it's not for casual conversation, especially not a forum - and it's not as if you can just medical supplies in a shop!

There are some people on here who ride the bike. And some who don't who are big beefcakes and most of us are more interested in doing things naturally - because taking the sort of supplements you're suggesting are not to be discussed in a trivial/matter-of-factly way. Just like any drug, it's abuse, and lack of knowledge can lead to very serious implications from, gyno and infertility as well as serious cholesterol and blood pressure increases to at worse, death. The list is large.

The natural supplements discussed in this thread will generally not cause any significant issues other than perhaps, headaches, flatulence or short term intolerances to them

There aren't that many bodybuilders on here either which is generally where messing about with your body's hormones is beneficial.

If you want to discuss it more openly join the facebook group or chat about it on forums that allow it. This is not the place for it.
 
That is very definition of cloak and dagger. The issue* exists, but nobody wants to talk about it. They prefer to brush it under the carpet and pretend the issue does not exist. Nobody wants or is permitted to openly talk about the subject, which is integral to sports supplementation.

*the issue being steroids.

However, the forums are run by OCUK and they make the rules, so I guess we must follow those rules.

Point taken.

Moving back onto the topic of supplements....

HMB: I've been using this stuff for about 2 months. I'm not sure if it makes any difference to my power or physique, but it certainly helps me sleep deeper. No question about it. Years ago, I tried Nytol to help regulate my sleep and that stuff was useless. I pulled an all-nighter (studying for exam next day) and completely forgot I took some. That was the last time I took that useless tablet. HMB is a great sleeping aid.

L Glutamine powder: I am currently trying this out. I have been on it continuously for about 2 months. I'm undecided about this. There was a thread made by someone who suggests taking purely L-Glutamine in the mornings, then not eating for at least 45 minutes. Apparently, this makes a person look better (better skin, etc). So I've been dosing as per his guide lines for the last week or so. I will let you know how I get on.

Whey protein: of course, this is a no-brainer.

Superpump 250 Max: I've tried out many pre-workout supps and this works the best, for me. It increases my heart-rate and makes me alter (improved focus). It also improves my physical performance.

ECA stack: when cutting, this is without doubt, the best stack I have used. The rest just don't work. This stack kills your hunger. It gives you a physical and psychological boost, allowing you to train at high intensity for extended periods of time. Ephedrine is banned by most anti-doping authorities and should not be overdosed on. I've been using this stuff for the last 10 years during my cutting phase with no problems (though I am careful on dosage).

Fine milled oats: I've had these in my protein shake and they mix well.
I have mixed feelings about oat supplements. If you are desperately trying to pack on mass at any cost (or involved in endurance sports), I'd certainly use this supplement, but for most purposes I can't see why I would use an oat supplement, vs "normal" food.
Freefaller gave me a good reply earlier on this thread regarding the benefits of oats. I would reply and state that most of what he stated can be achieved by a slice of bread. Furthermore, by adding some butter and tuna to the bread, you can easily turn that into a filling/tasty/healthy snack. You can't do this with the oat supplement.

Summary
IMO, caffeine is arguably the the best supplement for exercise. Pre-workout supps normally contain caffeine and some form of creatine.
Caffiene is also used in ECA stacks to remove fat from the body.
Whey protein is also a great supplement.

I feel that other supplements offer poor value for money, given the benefits they bring to the table. I'd rather spend the money on (real) food.

The above are my opinions of taking supplements for many years. I hope I haven't offended anybody. ;)

Steroids for personal use I have no issues with, but then you get a lot of people who say they're "not on them" who are, and have won things (i.e. Lance "I'm a scapegoat" Armstrong) who are despicable as they're playing victim despite cheating.

Now in a sport like professional bodybuilding where everyone is on the same page - sure, at least everyone knows they're in the same boat.


It's the naivety of people who think actors for example, get jacked without them - of course they use them, but they do not glamourise them (nor should they) because it will never be the same for the public, all these guys have private doctors monitoring their blood levels, health, and offering them certified medical supplies rather than backstreet made in Thailand dodgy crap. They're closely monitored - and have the time to workout 2x a day and eat the best foods.

Except ECAs are in a grey area too.... :/

Anyway, back onto the more salient points of this thread.

Caffeine has always been agreed to be a good boost pre work out.

Creatine is one of the most researched and accepted supplement out there - it's effectiveness varies depending on diet, exercise and how it is taken/stacked, cycled.

I do agree with you on the food > supplements - however, supplements have their place if you do eat a poor diet, or if you're not able to get your diet in check owing to whatever circumstances you are going through, or if you need to boost your diet / workout / recovery if it falls short somewhere. :)

HMB works even better stacked with creatine. It's an active metabolite within leucine which is vital for protein synthesis - and is really used for increasing LBM. I guess that's possibly why your sleep has improved - but it's not the biggest sell IMO for such a supplement.

Bread is actually pretty poor nutritionally speaking - especially the stuff you buy in the shops - it's highly processed, and sugar content is high.

Oats aren't a supplement, they are a food. :p

Whey protein doesn't "do" anything - it just provides your body with more protein. ;)
 
Agreed...but thermogenic pills can certainly assist in removing body fat.

For example, when cutting, I go through the routine of having my ECA stack. I can certainly cycle/run without it, but having the ECA makes me "believe" that my body is capable of super performance and helps me maintain high intensity, for longer. The caffeine also livens me up (very early in the morning - I hate mornings).

Yes that's obvious. However, I just have coffee - I don't like putting unnecessary chemicals into my body.

It has also been proven beyond reasonable doubt that ECA stacks work (speeds up metabolism, suppresses appetite).

So have other "special" supplements, as well as a lot of natural supplements, but also eating well, and doing the right sort of exercise.

Or what's even better is.... follow a healthy lifestyle, and not relying on chemicals to help you lose weight?

Is a supplement necessary. No
Is it helpful. Definitely...Absolutely. Yes.

1. Agreed.
2. Not that clear cut - "Can be helpful" yes, but it's not an absolute as you say - not by any stretch of the imagination.

Going the "quick win" route is just not the right way of going about it IMO.

Part of the fascination (and fun) of supplements is that you try them and have fun with them. The earlier posts above talk about using OAKG. Who knows if this will help their performance? But the users above are certainly experimenting to see if it helps.

IT's good that you're learning about these things - we all did it to a certain extent, some are going further than I'd like to go - but as long as you're aware of what you're doing, and don't think it's a magical solution to problems. However, the research of a lot of these supplements are endless - as many have some which support them and others that show just placebo like effects (i.e. nothing :p). However, everyone responds to things differently, and everyone's diets/lifestyles aren't the same.

Above all, remember, what works for 1 person, may not necessarily work for somebody else, so a level of experimentation is required. Once I find a supplement which works, I tend to stay with it. Caffeine is one the best supplements I have ever used and it just so happens to be available cheaply, in supermarkets.

Pretty obvious :p However, I wish you good fortune on your chemical experimentation. :)
 
I would want to make sure it's unbleached and un hydrogenated and good quality. But I don't buy cheap rubbish food. However I understand that not everyone has that mindset or ability. :) it's cheaper than the myprotein one. :)

This isn't a supp anyway. I consider it food. :)
 
It's cheaper than MP - yeah it's nice - you have to take it easy initially it's so nice you can easily eat 000s of calories! :D

However it's awesome for cooking with - and it's potentially thermogenic and little to no insulin response.
 
They cannot add the words if it isn't. I just like good quality foods. :)

None of the shops near me supply coconut oil - or at least not at a competitive price. So I buy it online.

It's no more stupid and ignorant than people blindly buying lots of supps. For me, I'm pretty confident my choices are above average and done with due care and intelligence. i.e. keeping away fro, unhuydrogenated, bleached and lower quality items. You do what you want though, I don't spend my money on supps, but on good quality foods. :)

Taste wise, there's not that much taste, and mainly used for cooking as an alternative owing to it's low to 0 oxidation and high smoke point, it also doesn't denature under heat. I don't often eat it by the spoon, but I do get a decent thermogenic reaction from it which is quite nice.
 
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Sooooo FF, I've been taking that Rhodiola Rosea you linked on Amazon now for a couple of weeks now, one tab a day in the morning fasted (as I don't eat till mid-afternoon most of the time).

I... think it's working. Cool stuff.

It's not a dramatic "kick" like caffeine. I take one in the morning and one midday - and I just like the effect it has on me, it's not a massive lift, but I certainly feel less fatigued and generally more relaxed but focussed at the same time. It won't fix depression or if you're in a **** place of course.

How has it manifested itself for you?
 
You can buy the powder as long as it's 3% rosavins you'll be reet.

If not I've got myself the following:

http://www.echemist.co.uk/p-viridian-maximum-potency-rhodiola-rosea-root-veg-caps

1. Composition


The plant rhizome of rhodiola rosea initially consists of many compounds including essential oils, fats, waxes, sterols, glycosides, organic acids such as oxalic, citric, malic, gallic, and succinic as well as phenolics including tannins and proteins. [1] The dried rhizome contains a mere 0.05% essential oil of which the most important subset for supplementation, Geraniol, consisted of 12.49% by weight.[2]

Geraniol's oxygenated metabolite Rosiridol and the compound Rosiridin (of which the former is an aglycon of) are considered the most active essential oil of Rhodiola Rosea supplementation.

Other non-essential oil compounds of Rhodiola Rosea include the polar water extracts such as polyphenols, flavonoids, proanthycyanidins, and gallic acid derivatives (amongst others).[3]. The water soluble component with the most biological activity in vivo was determined to be p-hydroxyphenylethyl-O-ß-D-glucopyranoside, more commonly known as Salidroside (also known as Rhodioloside or Rhodosin)[4]

The proanthocyanidin content of the water solubles consisted a great deal by weight (50-70%) and is credited for Rhodiola Rosea's potential anti-oxidant, anti-cancer, anti-inflammatory, anti-allergic, anti-mutation, anti-aging and liver health properties.[5]

Rhodiola Rosea is used above other species of Rhodiola due to it's comparatively high Rosavin (essential oil) content while still having an appreciable salidroside content.





Edit2. SHR-5


Rhodiola Rosea SHR-5 is a standardized extract of Rhodiola Rosea that is used in most human studies. When buying Rhodiola Rosea it is advisable to seek this specific standardization on the label.





Edit3. Pharmacology


In the body, Rhodiola Rosea (in regards to the Rosiridin, Rosiridol and Salidroside contents) has been found to be:

Neuroprotective against hypoglycemia[6], excitotoxicity from glutamate[7][8] and oxidation from beta-amyloids[9] and hydrogen peroxide radicals[10]


Cardioprotective by protecting cardiomyocytes against Ischemia[11][12]


Anti-diabetic by increasing glucose uptake into myocytes via activation of AMPK[13], as well as protecting neurons from periods of hypoglycemia, which is of interest to management treatment. Rhodiola Rosea may also act as a low-grade ACE inhibitor[14]


Hepatoprotective against tacrine-induced toxicity (although another species of Rhodiola was used in which the compounds Kaempferol is confounded)[15] and agaisnt acetominophen-induced toxicity[16]


Most of the protection effects of Rhodiola Rosea seem to be from the Salidroside component, whereas mood and cognition seem to come from the essential oil subsets of Rosiridin/Rosiridol.

The 'adaptogenic' effects of Rhodiola Rosea, alleviating the stress response, arise mainly from the ability of Rhodiola Rosea to minimize the cellular mechanisms responsible for initiating the stress response in the hypothalamus. This includes cortisol, protein kinases p-JNK, heat shock proteins, and some signaling proteins (DAF-16, FoxO) used in the stress response[17]

It is suspected that Rhodiola Rosea might be a valuable addition to treatment programs for depression due to it's lack of interactions with some other medications such as theophylline or warfarin[18]





Edit4. MAOI Activity


The Rosiridin subset of Rhodiola Rosea was found to act as an inhibitor of both Monoamine Oxidase A and B.[19]

This is one of the reasons Rhodiola Rosea may exert itself as a cognitive booster and anti-neurodegenerative agent, but caution should be taken when pairing any MAOI with other agents that increase monoamines such as dopamine or adrenaline.





Edit5. Cognition




5.1. Fatigue


In humans, Rhodiola Rosea has been shown on numerous occasions to reduce fatigue, improve mood, and alleviate stress in conditions as far ranging from exam periods,[20] general stress,[21][22][23] and stress-related depression.[24]





Edit6. Interactions with Exercise and Performance




6.1. Acute Usage


Effects on humans using Rhodiola Rosea as an acute ergogenic aid to increase exercise performance are mixed. With some results showing no significant difference[25][26] and some showing benefits.[27] It is suspected that this may be an issue of herbal potency (variations in active ingredients due to growing conditions) and a supposed bell-shaped curve of Rhodiola Rosea activity, in which it is ineffective in low doses and very high doses.[28]

One study using an acute dose of 3mg/kg bodyweight of SHR-5 (3% Rosavins, 1% Salidroside) noted that ingestion of the supplement prior to a 10k bicycle ride showed significantly reduced time to complete the ride (25.4 minutes relative to 25.8 minutes) and reduced heart rate during the warmup (136+/-17 relative to placebo's 140+/-17) but not during exericse, which alongside average power output and cadence only trended towards improvement.[29] This study was conducted in recreationally fit women, and the subjects reported less subjective fatigue after consumption of Rhodiola Rosea.[29]


Scientific Support & Reference Citations

Rosenroot (Rhodiola rosea: traditional use, chemical composition, pharmacology and clinical efficacy)

Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single dose administration

Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity

References
1.Panossian A, Wikman G, Sarris J. Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy. Phytomedicine. (2010)
2.Rohloff J. Volatiles from rhizomes of Rhodiola rosea L. Phytochemistry. (2002)
3.Phytoconstituents and Anti-oxidant potency of Rhodiola Rosea - A versatile Adaptogen
4.Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms associated with their Stress - Protective Activity
5.Comparative phytochemical characterization of three Rhodiola species
6.Neuroprotective Effects of Salidroside in the PC12 Cell Model Exposed to Hypoglycemia and Serum Limitation
7.Cao LL, Du GH, Wang MW. The effect of salidroside on cell damage induced by glutamate and intracellular free calcium in PC12 cells. J Asian Nat Prod Res. (2006)
8.Chen X, et al. Salidroside attenuates glutamate-induced apoptotic cell death in primary cultured hippocampal neurons of rats. Brain Res. (2008)
9.Zhang L, et al. Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells. Neurochem Int. (2010)
10.Chen X, et al. Protective effect of salidroside against H2O2-induced cell apoptosis in primary culture of rat hippocampal neurons. Mol Cell Biochem. (2009)
11.Zhong H, et al. Salidroside attenuates apoptosis in ischemic cardiomyocytes: a mechanism through a mitochondria-dependent pathway. J Pharmacol Sci. (2010)
12.Zhang J, et al. Salidroside protects cardiomyocyte against hypoxia-induced death: a HIF-1alpha-activated and VEGF-mediated pathway. Eur J Pharmacol. (2009)
13.Li HB, et al. Salidroside stimulated glucose uptake in skeletal muscle cells by activating AMP-activated protein kinase. Eur J Pharmacol. (2008)
14.Kwon YI, Jang HD, Shetty K. Evaluation of Rhodiola crenulata and Rhodiola rosea for management of type II diabetes and hypertension. Asia Pac J Clin Nutr. (2006)
15.Song EK, et al. Hepatoprotective phenolic constituents of Rhodiola sachalinensis on tacrine-induced cytotoxicity in Hep G2 cells. Phytother Res. (2003)
16.Wu YL, et al. Protective effects of salidroside against acetaminophen-induced toxicity in mice. Biol Pharm Bull. (2008)
17.The Adaptogens Rhodiola and Schizandra Modify the Response to Immobilization Stress in Rabbits by Suppressing the Increase of Phosphorylated Stress-activated Protein Kinase, Nitric Oxide and Cortisol
18.Panossian A, et al. Pharmacokinetic and pharmacodynamic study of interaction of Rhodiola rosea SHR-5 extract with warfarin and theophylline in rats. Phytother Res. (2009)
19.van Diermen D, et al. Monoamine oxidase inhibition by Rhodiola rosea L. roots. J Ethnopharmacol. (2009)
20.A double-blind and placebo controlled pilot study on the effects of Rhodiola Rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low dose regimen
21.Fintelmann V, Gruenwald J. Efficacy and tolerability of a Rhodiola rosea extract in adults with physical and cognitive deficiencies. Adv Ther. (2007)
22.Schutgens FW, et al. The influence of adaptogens on ultraweak biophoton emission: a pilot-experiment. Phytother Res. (2009)
23.Olsson EM, von Schéele B, Panossian AG. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Planta Med. (2009)
24.Darbinyan V, et al. Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression. Nord J Psychiatry. (2007)
25.Earnest CP, et al. Effects of a commercial herbal-based formula on exercise performance in cyclists. Med Sci Sports Exerc. (2004)
26.Colson SN, et al. Cordyceps sinensis- and Rhodiola rosea-based supplementation in male cyclists and its effect on muscle tissue oxygen saturation. J Strength Cond Res. (2005)
27.De Bock K, et al. Acute Rhodiola rosea intake can improve endurance exercise performance. Int J Sport Nutr Exerc Metab. (2004)
28.Perfumi M, Mattioli L. Adaptogenic and central nervous system effects of single doses of 3% rosavin and 1% salidroside Rhodiola rosea L. extract in mice. Phytother Res. (2007)
29.Noreen EE, et al. The Effects of an Acute Dose of Rhodiola Rosea on Endurance Exercise Performance. J Strength Cond Res. (2012)
30.Hung SK, Perry R, Ernst E. The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials. Phytomedicine. (2011)
 
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It's a very subtle effect, but I prefer the powder as it's usually more potent - but it's a faff and doesn't taste nice.

Chong is another advocate of RR. I do sometimes suffer stress/anxiety and I find RR does help abate those symptoms.
 
IT's just protein. But I like their supps and prices. :) I'd also rather give my money to people I trust. :) However my yearly protein purchase is due soon so I hope they do get themselves back on track!
 
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