Why is it an unfortunate side effect? Besides it doesn't happen to everyone anyway and I really doubt it has that much of an effect. Dont' get too worried about "genes", genes only come into play when we're talking professional and high-end sports people, for the average joe, i.e. all of us, it really means little. If you're big boned, or slight etc... most of us will be able to put on reasonable size and/or sculpt our bodies.