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What fixed the TDR's and PhysX issues for me is uninstalling the included version of PhysX and reinstalling the PhysX package from the Nvidia web site.
Please use this thread for further crash/driver crash reports
http://forums.overclockers.co.uk/showthread.php?p=28139905
350.12 is 100% stable for me newer ones both crash ingame or on desktop. Will retry them without chrome if i get time as normally chrome lives open on my desktop
So performance wise which is the best driver for GTA at the moment?
Regardless, nvidia need to release a solid driver and quickly.
I wonder if these crashes may actually do some permanent damage to the cards. Probably not like, but I don't like nearly £1k of gpus I have constantly recovering...