If I questioned whether Chelsea were a big European side, I assume you're taking the **** when you mention City?
As for the others, Utd are fine, Barca and Real will be fine providing they don't go on another massive spending spree and I have no idea about Juve.
Chelsea and City can meet the regulations but that's providing they massively cut back their spending (both on transfer fees and wages) and make significant improvements on their commercial deals. In other words, replace Drogba, Lampard etc with cheaper players on less money and sign commercial deals to rival Liverpool, Utd's etc.