I've not had the experience of using a native 4K screen, though I have heard there's less of a wow factor going from 1440p/2K to 4K,treated myself to a 4k Monitor too, however am not that impressed, prefer 1440p. Can't really tell the difference!
I'd take a picture but sick at the moment
whereas, going from 1080p to 1440p is very noticeable. I guess it's situation dependent and subjective, to an extent.